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Friday, August 14th, 2009

Mad Cow Disease and Variant Creutzfeldt Jakob Disease

BEWARE of “Mad Cow Disease” How is it Dangerous to Humans?

Mad Cow Disease or BSE (bovine spongiform encephalopathy) is a fatal progressive neurological disorder affecting cattle and caused by infection by an unusual protein agent called a prion. This harmful protein damages the central nervous system of cattle and causes degeneration in the brain and spinal cord.

The first noted instances of cattle with BSE infections occurred during the 1970s, the probable cause been infected meat and bone meal that was fed to cattle which may have contained BSE-infected products. The outbreak then reached epidemic proportions in the United Kingdomand eventually spread throughout the cattle industry. By the end of 2008 more than 184,000 cases of BSE in over 35,000 herds had been confirmed in the UK alone, with around 4.4 million cattle slaughtered to cull the spread of the disease.

BSE was shown to be transmittable to humans through the ingestion of bovine meat, especially the brain or spinal chord. The human strain of the diseases is called new variant Creutzfeldt-Jakob disease (vCJD) and is deadly killing nearly 200 people in Britain alone. The long incubation period of the disease, which can be up to 40 years means this number can rise. In a few cases, the disease was inherited from an infected parent. CJD can become fatal within months or even weeks. Human to human transmission occurs when the patient is exposed to an infected person’s brain or spinal cord either through medical transplants or contaminated equipment.

CJD Symptoms include rapidly progressive dementia, personality changes, memory loss and hallucinations. CJD sufferers also exhibit physical signs of infection including uncontrollable limb movements, slurred speech, visual disturbances, changes in posture and in some cases violent seizures. Symptoms may be similar to other degenerative diseases like Parkinson’s or Huntington’s disease.

There is no single diagnostic test for CJD but a neurological exam is performed on the patient to rule out other diseases. Confirmation of the disease is usually through a brain biopsy, in which a small tissue of the patient’s brain is removed for checks. It is a potentially dangerous operation and there is a small risk that the medical professionals handling the tissue may themselves become infected, so this procedure is often discouraged unless necessary to rule out other factors. A safer test is the examination of a certain spinal fluid in the body, with other tests been developed.

There is no cure for CJD, and much of the medication available to treat it has not been effective. Current treatment procedures are aimed at reducing the harmful symptoms and making the patient comfortable.

12 Responses to “Mad Cow Disease and Variant Creutzfeldt Jakob Disease”

anthony bergen Says:

I served in Germany with the Army from 1981 – 1983. A few months ago I went to donate blood. I was screened and was asked if I was ever in Europe sine 197? I answered yes and I was immediately told I my blood could not be taken due to the fact I was potentially exposed to Mad-cow disease while in Europe. So now I wonder how many soldiers were potentially exposed to this and why hasn’t anybody said anything about this. Will I get sick and die of this terrible disease? Have any other soldiers gotten sick and died of unknown causes? Is this being kept a secret?

scharabo Says:

Likely most of the 56M population of Great Britain was exposed to beef from MCD-tainted animals. However there have only been about 200 documented cases of vCJD (which is exactly like CJD, just it occurs in younger people). My theory is these 200 would have acquired full CJD later in life, exposure to MCD just triggered it early. Since your changes of dying from CJD are about 1/1M, I wouldn’t worry much about it. After all the U.S., which likely is amoung the top beef consuming nations, hasn’t had a single native case of vCJD.

cheri Says:

That is not true. My uncle died from CJD about 20 years ago in Bowling Green Ky. I’m sure he was not the only one.

KAOS Says:

There are a number of reasons that we do not have BSE problem in the US. I beleive the major reason is we do not have a closed system like the UK (an island). The meat and bone meal and other rendered products, if became contaminated would be diluted in the US, and not circulate in increasing levels as likely happened in the UK. In addition, the US government has put a number of safeguards into cattle feeding systems, including prohibiting the feeding of mammalian protein (meat and bone meal, etc). New variant CJD is histopathologically distinct from genetically linked CJD, although it is correct to state that it often occurs in younger patients.

The fact that the Red Cross will not accept blood from those living in the Europe for an extended period is an incredibly cautious tactic. But one that the blood recipients likely appreciate.

sarah Says:

In 1992, my father (a native New Jersey boy who spent his adult life in Texas and California) died of CJD. No one in my family is allowed to donate blood due to our relationship to him, and my mother has since learned of hundreds of CJD fatalities in America through internet networking. The fact that most people still believe that there have been no American CJD fatalities, leads me to believe that the beef industry is a very strong lobby group. As for me, I still eat meat due to the fact that if it’s already dormant in my system due to a burger I might have shared with my Dad at some point in my childhood, there is nothing that is going to hurt or help the process now. Has there been secret-keeping about the issue?…..I definitely think so. A panicked public is something the government always seeks to avoid.

Ellissee Says:

40 years to incubate? So, if one traveled to England in 80’s and ate beef – would not know yet. Great. Mad Cow has been found in U.S. and it’s kept quiet, saying only 1 cow among all others, a few times, and they ‘found the source’ and we’re safe – how many really believe this.

Maureen Holder Says:

I am a Registered Nurse. While working in Ft.Lauderdale, Fl 1994, we admitted a man 40 years old,a professor, healthy except for the fact that he was having some problems with his short term memory. I asked if he had been out of the country, to which he answered yes, South America and also England ! Of course we thought he picked up something in S.A. He degenerated quickly, and in 6 weeks he was dead, not knowing who he was, where he was nor did he recognize anyone. He had CJD which sent us all to our Nursing Books as we were not familiar with the disease at that time. It is very freightning to observe. MKH

unc s Says:

What about passing it through milk?

Gwen Says:

CJD is also known to be present in wild game populations such as venison and elk. So avoiding beef is not enough. Also, though obviously much rarer, people are thought to have caught it in rural areas from eating squirrel brains.

I understand that it can be diagnosed from tonsil tissue; in the UK they are collecting tonsils from children having tonsillectomies…and finding high rates of infection. I agree that the media are avoiding/downplaying the topic.

LIzzy Says:

Anyone interested should read “Deadly Feast,” a book by Richard Rhodes.

James Derwin Says:

Milk question. India found prions in cows milk! However, they couldnt determine if it was infectous or not. I dont eat hamburger, but I do eat well done steak, usually organic.

MollyMac Says:

Because of the Federal HIPA regs., I won’t say where this happened – only in N.E. A woman was brought into our surgical unit with a rictus grimace and shortly afterwards followed the CDC with their black suits and briefcases. Our staff was stunned at the diagnosis and her family was interviewed for days. Assigned to a Hospice room (large & private)it overflowed with family and the interrogaters;they went back years with them family over meats she ate/where she shopped/etc. She died, and then not another word was spoken of it either on the news, in the paper or even on our floor. It IS being downplayed.

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