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Monday, August 17th, 2009

Wrongly Diagnosed with Multiple Sclerosis? Take a Peek at the Early and Secondary Symptoms of MS

Multiple Sclerosis (MS) is an auto immune disease that affects the brain and spinal cord and in which the body’s immune system, which normally attack bacteria and viruses, attacks a person’s central nervous system instead. MS also leads to inflammation of parts of the infected brain and spinal cord causing damage.

The inflammation stops the affected nerve fibres from functioning properly and symptoms develop, but this then clears and the never fibres heals and starts working again. But this inflammation may be repeated and leave small scars, called sclerosis, which permanently damage the nerve fibres. Someone with MS will have many (multiple) areas of small scarring that develop in the brain and spinal cord.

MS can begin at any age, with early signs occurring between the ages of 20 and 40 and more common in women.

Symptoms depend on which part of the brain or spinal cord is affected. There may be one symptom in one area of the body or several symptoms in several areas. Common symptoms include numbness or a tingling sensation on parts of the skin which is most common during a relapse, muscle paralyses that affects mobility, problems with balance and co-ordination, problems passing urine, tremors or muscle spasms, erectile dysfunction for men, partial loss of vision or difficulty speaking and mood swings.

MS goes through stages of development. There’s the relapse-remission form of the disease, in which a person suffers from a bout of symptoms that last days or weeks, then the symptoms disappear again for months leaving a person on remission. More relapses followed by remission then occur over time. The frequency of relapses varies, with one or two relapses a year been typical. The relapse-remission pattern can last for several years and symptoms may also change during each relapse.

As MS develops, some of these symptoms may become permanent due to accumulation of scar tissue in the brain and the gradual nerve damage that occurs. Symptoms also worsen over time and secondary symptoms like urine infections, contractures and osteoporosis may be present. People with relapse-remitting MS will usually develop secondary MS symptoms after 15 years.

In primary progressive MS, there is no relapse-remission pattern, and the symptoms become worse from the beginning and the patient never recovers. Benign MS indicates only a few relapses in a person’s lifetime with no permanent symptoms.

MS may be hereditary with higher chances of developing the disease in those with a family history. It can be difficult to diagnose as MS symptoms are present in other diseases and there are no definitive tests to prove the existence of the illness, but a firm diagnosis can be made after at least two relapses. There are also tests that can indicate the possibility of MS, these include MRI scans of the brain that can detect small areas of inflammation and scarring, or a Lumbar procedure in which a needle is inserted in the spinal cord to measure protein levels.

There is no cure for MS, but treatments are available to alleviate the symptoms and treat relapses. Immunomodulatory drugs are used to reduce the number of relapses, steroids reduce inflammation and anti-spasm, pain killers and anti-depressants may also be prescribed. Physiotherapy, speech therapy and psychological therapy are also being recommended.

22 Responses to “Wrongly Diagnosed with Multiple Sclerosis? Take a Peek at the Early and Secondary Symptoms of MS”

tana Says:

Mood swings? This is the first I heard, must be the result of trying to get people to understand what is wrong with you. And that sounds like a reasonable reaction to some very ignorant behavior, not a symptom of a disease. May be inherited. Since no one knows what causes MS, it is foolhardy to say something like this. I was diagnosed 35 years ago.

marty pedranzan Says:

found your article interesting…my wife developed primary progressive MS at the age of 39…just collapsed one day and loss use of her legs…was tested at the hospital using the lumbar method you spoke of and a mass of scherosis was detected at the top of her spine..she had been previously experiencing some of the early signs that you spoke of…however doctors were unable to detect anything in previous tests..including MRIs.she was diagnosed with fibromyalgia originally.she fought a galliant fight…but lost her life at the age of 42. she developed other problems such as bed sores and had numerous infections from her cathiter and ultimately died of pneumonia.I often wonder had a more earlier correct diagnosis been made, if she would be here today.her neurologist said it was one of the most severe cases he had seen.thanks for the article …I hope it will help other people that are affected by this.I miss my wife still very much.

todd mccagg Says:

Interesting article and most of it sounds pretty much right on the button. That said, every person w/MS has different problems and or different degrees of trouble with their everyday tasks. I myself was finally d/xed with MS back in 2000 after 15yrs of drs telling me it was all in my head and or that I was exaggerating my symptoms esp the pain. Every dr then and even now understands the type or amount of pain we have (for me its 24/7)and they want to just blow it off with some tylenol. My problem with my MS is that it went untreated for 15 long yrs that the therapies out there are totally useless on me. Ok yall I dont mean to rant over and over again so Im ending here, but feel free to get back to me, Rev.Todd M., your rolling preacher who refuses to let the MS completely take over my body!!! Just like I told the MS when I was officialy d/xed “it can stay or it can go, but this is my body so its my way or the highway” Its still here but ah we get along………………..

Me Says:

Mood swings are definitely a symptom of MS… happy one minute… mad the next. I don’t know if its the MS that causes it, or the medication (it is said that mood swings can also be a side effect of the injections). So who knows for sure, but mood swings are a valid symptom for an MS patient.

andy Says:

what does this article have to do with “wrongly diagnosed”

Angela Says:

Hi Tana,
I have had MS for 18 years. I have been to many doctors and read many studies on MS. While scientists do not know exactly what causes MS, there are recurring factors for MS patients, one of which happens to be heredity. It does increase one’s chance of getting MS if someone in their family has it. Other indicators that are proving to be associated with MS are diet, stress, and environment. Those people with MS are showing to be deficient in vitamins B and D. There are a significantly lower amount of MS cases near the equator where vitamin D is gotten from the Sun. Also, people with diets high in fat seem to be common in those who are diagnosed with MS. I hope you find this information helpful. I have spoken about MS for some years now and have gathered this information along the way.

Sincerely,
Angela

Angela Says:

Marty,
Sorry to hear about your wife. It must have been very shocking for both of you for her to be healthy one day and disabled the next. Your wife’s case is rare and thank God we have the medicines to help stop progression as well as meds to help with the symptoms. I’m not sure when your wife passed but the discoveries made in the last 10 years have been amazing…God Bless you and your family.

Susie Says:

I’m so sorry to hear you say how you think this is an ignorant behavior. They have finally come out to say that depression is a norm for MS patients along with fatique. The suns’ heat alone can be a real gut wrencher, losing balance and the ability to think and speak. Depression alone has the ability to give some one a mood swing, suicide must be one of these mood swings. I feel sure if you were to speak to a Neuro. specializing in MS they would say there are many, many undiscovered side affects of MS. My diagnoses was 15 years ago, there are new realizations every year. I never know what tommorrow is going to bring, my goal is to stay as upbeat a possible and not be around people who think I’m faking it. I wish you well and much luck.

marie Says:

Mood swings are quite familiar to me. I began having anxiety attacks and later bouts of depression. mood swings are not necessary from minute or one hour to the next. They can be weekly or monthly as well. I think you face mood swings normally whether you are diagnosed with an illness or not but I do know that I experience mood swings.

maria Says:

I have long suspected that I may have MS. I’ve had the classic symptoms (numbness and tingling in my hands and feet,absolutely no tolerance to heat, extreme fatigue, stiffness/spasticity, brain fog, pain and lately I also have excessive daytime sleepiness)
These symptoms are getting worse by the day. I have yet to be diagnosed because when I first started experiencing all this, I went to the rheumotologist asking to be tested for MS, only to be told I am making it a big problem for no reason, and maybe I was depressed and looking for attention. I protested his ridiculous diagnosis (I was NEVER tested), and I told him that I was sick and tired of being sick and tired. Needless to say, I never went back to that quack.
Now I am waiting for my new health insurance to start, and I am looking for a new rheumotologist.
Does anyone have any advise on how I can get a new doctor to listen to my complaint and symptoms? The last few days have been so very difficult–I am not feeling well at all.
I live in NYC–if someone knows of a good MS specialist in the NY area, I will really appreciate if you pass his name and phone number to me.
Thank you and Godbless.

Deanna Close Says:

I suffer from mood swings and my neurologist states that it comes from the number of lesions on my brain, their location, and how they respond during a relapse and/or remission. I have had MS for 20 years.

Jody Says:

Some theories postulate a slow acting virus, at puberty I experienced a spike fever 98.6 up to 104.5 within an hour and back to normal 45 minutes after the episode started. After that, I experienced sporadic EXTREMELY SEVERE vertigo and motion sickness. The lack of balance became more pronounced yet nothing ever showed on the tests until I got fed up with my Doctor, who anounced the FIRST time I saw him, with only the benifit of an exam of my reflexes, that I either had a brain tumor or MS and sought another who informed me that because the 1st doctor (a hack) had ignored test results from an ENT and not followed up there was now nothing that could be done to diagnose the problem until it showed up in an MRI. Everything I’ve been through folows the relapsing-remitting type of MS, with slow but progressive increase in the chronic nature. I’ve stopped “spinning” but I constantly feel as if I’m moving, sometimes it seems like in every direction at the same time, I can’t track objects with my eyes, on TV at intersections. I have what are called alpha intrusions in my sleep cycle that the sleep specialist couldn’t explain. The resulting deprivation of REM sleep, and you are not aware of it because you don’t wake up completely, sets you up for depression that couples with the anger and frustration of finding SOMEONE to take you seriously that leads to anxiety, increased stress sensitivity, decreased ability to cope, and mental health “professionals” who tell you that you “just need to stop taking all this medicine” without bothering to find out WHY you’re taking it – palliative treatment of chronic and VERY REAL symptoms, instead of recognizing that you have a problem that has defined definition and need help in coping with the mental stresses that result from it. IT TOOK 20 YEARS FOR ANYTHING TO SHOW UP ON THE MRI. I gave up for many years and just lived with it, but now I have the name of a Doctor with a good reputation with a friend who has acute MS, and symptoms that have reached the point that they affect my quality of life. MS or not it is a demyelinating process. NOW IF HE CAN JUST MAKE MY WORLD MOVE IN SYNC WITH THE REST OF THE WORLD.

Partner Says:

Actually, I have read that now whenever someone is diagnosed with a mental illness that they need to be evaluated for MS. The bipolar disease is very real and the hardest to deal with – especially for the family. My spouse has bipolar and has MS although still walking and working (barely on the latter). It has nothing to do with being diagnosed with an awful disease (depression that one would expect from any tragedy), rather, it’s the brain not functioning right. Mild dementia (not Alzheimers or old age dementia) is fairly common too in Ms as parts of the brain are fried. Unfortunately, most neurologists don’t admit to these comorbid diseases. We went round and round … finally got the bipolar diagnosis then the MS diagnosis. Unfortunately, the treatment for MS makes bipolar worse and treatment for bipolar makes MS worse. Still in the dark ages on all that.

Jackie Holloway Says:

I was diagnosed in 1995. My first few tries with doctors did not work. I met this lady who told me to go to the ms clinic at UC Irvine. I finally got help and support. The ms society can help direct you to a good doctor. Most people just need a little nudge in the right direction to find good help in getting a diagnosis. My heart goes out to all the people who need help. In southern california we have a very good ms society support system. I hope everyone gets the help and support and diagnosis that they need.

kitty Says:

In the event that you may have missed the recent news of a new Multiple Sclerosis Drug
created, has completed the requisite 3 clinical trials and awaiting FDA approval. It is
the product of The HUMAN GENOME SCIENCES RESEARCH COMPANY – A biotech company
in association with NOVARTIS PHARMACEUTICAL CO.

There is a Website for this Biotech Company. This company also has a listing on the
website for the NYStock Exchange,with background information on this new MS drug.

kitty Says:

In response to Maria’s message, NY Presbyterian Weill Cornell Medical Center is known to
have specialists in Multiple Sclerosis in their Neurology Dept.
The Neurology Dep’t for further information can be reached at 1-212-746-5938

NY Presbyterain Weill Cornell Medical Center 525 East 68th St, (York Ave and 68th) NYCity
1-212-746-5454

Debbie Says:

My 27 yo daughter was just diagnosed with MS and I am terrified of what today and all the tomorrows hold for her! She has three young children (youngest just turned 1) that need constant care and she’s tired and in great pain all the time. She hasn’t started the injections yet — that will be next week – but she has mood swings, limbs that don’t want to move, fatigue and blurred vision (for the last year – thought she needed glasses) One day last week she couldn’t see for a short period of time and got really scared. (So, does that mean she’s more advanced or it’s just in that part of her brain?)

All of this started with her getting sores on her face that wouldn’t heal then the one above her eye abscessed. She also had a lump in her jaw that was causing her problems and she was just feeling lousy and in pain. So she went to HF Main and a lady (nurse?) (social worker?) really “heard her” and immediately applied for emergency insurance. They discovered she had mono and fluid on her neck with was eventually drained. When she mentioned that it felt like something had burst in her head, an MRI was immediately ordered which showed there was something abnormal in her brain. At first, it was said that it was like a nodule but still not understanding what – they told her they thought it was MS. She came home that evening and said they think I have MS. Just like that sentence reads…..She wasn’t crying or angry or even upset because she didn’t know what it was. When she looked it up on the internet the next day, she asked my mother (her grandmother) if what it said was true. Then she went into denial. No one was to know, if she didn’t go and hear the final diagnosis it wouldn’t be true, she cancelled and rescheduled her neurology appointments but did have the second MRI late last week.

It and the neurologist confirmed the diagnosis today. I was supposed to go with her to the appointment to take notes and lend support but the appointment was suddenly changed from Wednesday to this morning and I couldn’t be reached in time.

The next step is for the nurse to come to the house and giving and teaching her how to give herself injections. (What type of injections are these?) She has new sores on her elbows and is running fevers! They have her on strong pain pills, muscle relaxants and antibiotics right now. I feel like I really let her down when she needed me the most.

I think looking back with the little I know about MS that she’s probably had it for at least a couple of years. She’s had so many illnesses and pain that no one could pinpoint why. It’s scary and I’m afraid for us all!

I’m sorry for the length of this “comment” but we could use your advice, support and wisdom because denial, anger and crying isn’t going to make this unreal or go away. And, I know being proactive is the right approach but how do you get there, what do you do to fight it so its progression is slowed way down or it’s in remission more than not?

THANK YOU

Debra Says:

Marty P,
Thank you for sharing your story about your wife. I am sure you do miss her still to this day. Sweet of you to come to this page, read and comment. When I was reading your post, I too, was wondering if she had been diagnosed when she first started going to the doctors would that have helped her. I have never read or heard of such a case or quick death. I had my diagnosis within 6 weeks 15 years ago. My doc was fabulous at diagnosing his patients pretty quickly, that heard from medical staff. Anyway Marty May God bless you, you seem to be a nice fella.

Brennan Says:

It seems to me that any autoimmune illness, or those of the central nervous system or autonomic nervous system for that matter, are an indication that the blood/brain barrier has been breached. That would mean the brain is under fire from the invasion and symptoms that “appear to be” those of a mental illess like bi=polar are inevitable. Depending on which area(s) of the brain is being attacked the manifestation via symptom varies by individual.

Mary Fox Says:

So interesting. At times, I have wondered if I may have MS. On the left side of my brain, near temporal area, is some scar tissue. The neurologist does not know where it comes from. I am a 76/77 yr. old female and had first seizure at age 73 and 2nd one at age 76. Unconscious for a few days, I didn’t know what happened. Sodium & potassiom low in both cases and newly diabetic of almost 400 glucose. I ate 1/2 gal of ice cream, a cinnamon bun and half of danish. went to sleep and cannot remember anything for a few days. Very swollen tongue. Unable to eat or drink and tongue bitten immensly. The MS symptoms for MS are familiar to me, but with rotator cuff tears and pain up side of neck, and head and tenderness in back of head, when touched. Could it be MS?

Mary Fox Says:

I was thinking that I may have CHIARI, like my 14 yr. old grandson and 18 yr. old granddaughter, brother & sister. Boy had back of head surgery with section on bone replaced with goat gut or something. Girl is on meds for headache, most common symptom. She may need surgery. We Live in RI and they both go to RI Hospital and also in Boston somewhere. Can’t wait for your response. Meanwhile, I just take it easy and keep busy mentally with hobbies. Calligraphy & genealogy. Oh, I do have some tremors in just fingers with tingling in forearms and hands with burning feeling and it is also in the feet. bottom seems to burn, but not for long. thank you for your patience. Mary

kathy Says:

ok, maybe someone out there can help me. I am 51, was diagnosed with Mixed Autoimmune disorder, which means that i have symptoms of an autoimmune type disease, but my rheumatologist says it hasnt shown itself yet. I have had many symptoms the last 15 years… but now am experiencing new(about 6 months) ones. when at rest (mainly) i have muscles that jump/fire/jerk. they can be anywhere, but tend to be lower extremities, I mean my whole body moves when it happens. also, at times, my arm or hand will jerk, which can cause it to literally look like i waved my hand. tends to be on the right side vs left. also can feel muscles vibrating at times and that is anywhere, even abdomen. at times, i think it is my cell phone vibrating at my waist…. very weird. my vision is decreasing somewhat but I am old and have increased my readers strength. over the last month or so i have started having awful cramps in my calves. usually just one, but a couple of times both legs. they stay sore for days.

I must add I am a nurse and am starting to worry because they seem to be progressing.

anyone out there with any feedback.

kathy

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